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Pharmacogenetics is a branch of science that combines pharmacology and genetics. It is a widely known fact in healthcare that our genes affect our response to medications. A medicine can be highly effective in treating some patients while others will not benefit from it or even suffer adverse reactions.
The rapid evolution of gene technologies in recent years has made genetic testing fast and affordable, making it possible and even cost-effective to utilise pharmacogenetic testing in all clinical settings – not only when treating cancer or rare, genetic disorders. Many common medications such as statins, codeine and a large number of antidepressants and antipsychotics are affected by pharmacogenetics.
Before, doctors chose medication based on the diagnosis and standard treatment guidelines, but now various characteristics of the patient themselves are also becoming a crucial factor in the medication decision-making. The knowledge that a patient is a poor CYP2C19 metaboliser can be as important as the knowledge that they are allergic to penicillin, and this knowledge can guide the doctors in choosing the most suitable medication for the patient individually.
As healthcare is shifting from the old one-size-fits-all model to more personalised medicine, healthcare professionals need tools to help them navigate the abundance of pharmacogenetic information. To be routinely applied to clinical practice, the information needs to be actionable, easy to understand and available exactly when and where it is needed.
Our pharmacogenetic recommendations are based on the synthesis of information from several sources, such as CPIC (Clinical Pharmacogenetics Implementation Consortium), DPWG (Dutch Pharmacogenetics Working Group), FDA (U.S. Food and Drug Administration) list of pharmacogenetic biomarkers, summaries of product characteristics (SPCs) and published, peer-reviewed research articles of high quality. Our board of medical professionals with expertise in pharmacogenetics continuously follows new research and recommendations and curates the information, taking into account the quality of the studies and level of clinical evidence. The pharmacogenetic recommendations are updated when new scientific articles and guidelines are published.
Our solution provides healthcare professionals with actionable recommendations that are easy to understand and also easy to find whenever they are needed. It allows pharmacogenetics to be seamlessly integrated into your system, other clinical decision support tools, and the routine workflows of the healthcare staff.
Abomics, Abomics PGx, GeneRx, GeneAccount are registered or non-registered trademarks of Abomics Oy in various countries.